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An exceedingly serious allergic reaction to this drug is scarce. On the other hand, get healthcare enable instantly should you notice any symptoms of a significant allergic response, including:

Drug withdrawal syndrome Ahead of beginning treatment with any opioids, a discussion need to be held with patients To place set up a withdrawal method for ending cure with oxycodone.

Conversion from Methadone to OXYCONTIN Normal evaluation is of unique worth when converting from methadone to other opioid agonists.

Use of opioid analgesics for an prolonged time frame throughout pregnancy may well bring about neonatal opioid withdrawal syndrome [see Warnings and Precautions (five.4)]. There won't be any readily available facts with OXYCONTIN in pregnant Females to tell a drug-connected possibility for significant delivery defects and miscarriage. In animal copy research, there was no embryo-fetal toxicity when oxycodone hydrochloride was orally administered to rats and rabbits, throughout the duration of organogenesis, at doses one.

The concomitant usage of opioids with other medications that have an effect on the serotonergic neurotransmitter program has resulted in serotonin syndrome.

• There's a chance of abuse or addiction with OxyContin. The chance is larger if you are or have already been addicted to or abused other medicines, Road medications, or Liquor, or if you have a historical past of mental troubles.

Specific medicines should not be employed at or around click here the time of consuming food items or consuming specific sorts of food items given that interactions might happen.

If withdrawal symptoms crop up, it may be important to pause the taper to get a length of time or increase the dose with the opioid analgesic towards the prior dose, after which you can progress having a slower taper. In addition, Consider sufferers for any changes in temper, emergence of suicidal views, or utilization of other substances.

Oxycodone is really a generic prescription drug. A generic drug is an exact copy in the active drug inside of a brand-identify medication. The generic is regarded as just as Risk-free and efficient as the initial drug. And generics have a tendency to cost a lot less than model-identify medications.

OXYCONTIN is contraindicated in people with known or suspected gastrointestinal obstruction, like paralytic ileus.

The existence of other health-related problems may have an effect on using this medication. Ensure you notify your physician For those who have another healthcare troubles, Primarily:

Opioids are sought for nonmedical use and are matter to diversion from authentic prescribed use. Take into consideration these dangers when prescribing or dispensing OXYCONTIN. Methods to scale back these pitfalls include things like prescribing the drug in the smallest suitable quantity and advising the client on cautious storage of the drug over the training course of cure and the proper disposal of unused drug.

Observational studies have shown that concomitant utilization of opioid analgesics and benzodiazepines raises the danger of drug-relevant mortality compared to usage of opioid analgesics by itself.

The above mentioned information and facts is intended to dietary supplement, not substitute for, the expertise and judgment of the wellness treatment Skilled. You'll want to talk to your health and fitness treatment Experienced ahead of having any drug, changing your diet regime, or commencing or discontinuing any class of remedy.

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